​The National Library collects many illustrated Megillot Esther. The most unique megillah in the library is also the most ancient, perhaps one of the earliest extant megillot. It was written and illustrated by Moshe ben Avraham Peshkarol in the Italian city of Ferrara in 1616 and is over four meters long and 27 centimetres tall. According to the biographical information it includes, it was written for Mordechai ben Eliyahu Halevy from Brescello, a small town near Parma in northern Italy.

The Megillah is very colourfully decorated with blue-green columns dividing it into sections. Between these columns is a vase from which emerges a branch adorned with flowers. Each column rests on a rectangular base on which there is an illustration of an animal, bird, or plant. At the top of each page there is a figure of a man in full attire. Above the columns are illustrations of situations described in the text which demonstrate contemporary Italian, and not the original Persian, materialistic culture (clothing, food, dwellings, etc.).